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Jurnal Farmamedika (Pharmamedica Journal)

farmamedika
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Published by Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

ISSN : 25026011 EISSN : 26864487 DOI : https://doi.org/10.47219/ath

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

Jurnal Farmamedika dikelola oleh Lembag Penelitian dan Pengabdian Masyarakat, Sekolah Tinggi Teknologi Industri dan Farmasi Bogor. Frekuensi penerbitan jurnal sebanyak 2 kali dalam satu tahun pada bulan Juni dan Desember. Kategori tulisan berupa hasil penelitian dari peneliti maupun akademisi dalam bidang Kimia Bahan Alam, Analisis Farmasi, Farmakologi dan Toksikologi, Kimia Medicinal, Biologi Molekular dan Bioteknologi, Farmakoterapi, Farmasi Klinis, Farmasetika dan Teknologi Farmasi, Biologi Farmasi, Manajemen Farmasi, Farmakoekonomi.

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi

Articles 7 Documents

Search results for , issue "Vol 3 No 1 (2018): Jurnal Farmamedika (Pharmamedica Journal)" : 7 Documents clear

FORMULASI DAN AKTIVITAS ANTIBAKTERI SEDIAAN GEL HAND SANITIZER DARI EKSTRAK ETANOL BIJI MANGGA HARUM MANIS ( Mangifera indica L.) TERHADAP Escherichia coli DAN Staphylococcus aureus Harry Noviardi; Herson Cahaya Himawan; Rina Anggraeni
Jurnal Farmamedika (Pharmamedika Journal) Vol 3 No 1 (2018): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Mangifera indica L. is a plant that has antibacterial activity. One of the plant‟s parts that has antibacterial activity on mango is the seed. Natural antibacterial content in the form of tannins contained in ethanol extract of Harum Manis mango seed is considered being effective towards Escherichia coli and Staphylococcus aureus bacteria, which are the main cause bacteria in diarrhea and other skin infections. The objective of this study is to obtain a good and effective formulation to remove Escherichia coli and Staphylococcus aureusbacteria in order to produce natural hand- made antiseptic gel preparations. The diameter of clear zone produced by gel preparation of hand sanitizer ethanol extract of mango seed on Escherichia coli bacteria with gel concentration of 2; 2.5 and 5% respectively - 10.86, 1.74, and 13.15 mm, while on a positive control, it is 7.47 mm. On the other hand, the diameter of clear zone in Staphylococcus aureus with gel concentration of 2; 2.5 and 5% respectively - 10.14, 10.58, and 12.83 mm, while on the positive control, it is 7.43 mm. Based on Anovaone way test followed by Duncan test show a significant difference (significant effect) between the concentration. It can be concluded that the preparation of 70% ethanol extract gel having antibacterial effectiveness towards Escherichia coli and Staphylococcus aureus and effective gel preparation evaluation results are at 2,5% concentration

EVALUASI PENYIMPANAN OBAT DAN ALAT KESEHATAN DI APOTEK RESTU FARMA Muhammad Afqary; Febi Ishfahani; M. Tirta Rachman Mahieu
Jurnal Farmamedika (Pharmamedika Journal) Vol 3 No 1 (2018): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Storage is one of important process in the management of drug and medical devices.This study aims to evaluate the storage system of drug and medical devices in the Restu Farma Pharmacy. This is a descriptive research which carried on by direct observation and interview. This research was evaluate arrangement of drugs and medical devices in Restu Farma Pharmacy. This research show that in Restu Pharma Pharmacy the drug and medical devices were arranged by type of drugs (tablets, syrups, intervereous liquid and injection). The Restu Pharma Pharamcy‟s warehouse was as the drug and medical devices in Restu Pharma Pharmacy ware house was arrange by type of drugs (tablets, syrups, intervereous liquid and injection).The storage in the warehouse at 75% and the service room at 85% is [compliance with Permenkes No. 73 of the years 2016 about standard of pharmaceutical care at pharmacy.]

AKTIVITAS INHIBISI α-GLUKOSIDASE DARI EKSTRAK AIR DAN ETANOL DAUN SIMPUR AIR (Dillenia suffruticosa (Griff.) Martelli) Sitaresmi Yuningtyas; Anna P. Roswiem; Erfina
Jurnal Farmamedika (Pharmamedika Journal) Vol 3 No 1 (2018): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Diabetes mellitus is a disorder of carbohydrate metabolism which characterized by hyperglycemia conditions. One of the mechanism from oral hypoglycemic drug is inhibition of α-glucosidase activity. Dillenia suffruticosa (Griff.) Martelli, known as "simpur air" has been used to treat diabetes mellitus. This study aims to determine the inhibition activity of α-glucosidase enzyme from water and ethanol extract simpur air leaves. Simpur air leaves extracted with water and ethanol 70% using maceration method. Parameter evaluated in this research were phytocemical screening and alpha glucosidase inhibiting (AGI) activity. The results showed that the active compounds in water and ethanol extracts were flavonoids, saponins and tannins. AGI activity in water extract from simpur air leaves at concentrations of 1%, 1.5% and 2% were 1.49%, 2.76% and 3.91%, respectively. AGI activity in ethanol extract from simpur air leaves at concentrations of 1%, 1.5% and 2% were 92.10%, 98.10% and 118.30%, respectively. While the AGI activity from glucobay were 99.50%. The optimum of AGI activity was in 1.5% ethanol extract. This AGI acivity which was not significantly different (α<0.05) from the 1% glucobay.

SINTESIS NANOPARTIKEL PERAK MENGGUNAKAN EKSTRAK KULIT BAWANG MERAH (Allium cepa L.) DAN UJI AKTIVITAS ANTIBAKTERI TERHADAP BAKTERI Staphylococcus aureus Triyani Sumaiti; Devi Ratnasari; Dinda Dwi Mutiani
Jurnal Farmamedika (Pharmamedika Journal) Vol 3 No 1 (2018): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Synthesis of silver nanoparticle and determination of its antibacteial activity for Staphylococcus aureus were studied in this research. Silver nanoparticle (NPAg) were synthesized using method green synthesisby reacting extract peel of onion (Allium cepaL.) and silver nitrate (AgNO3). NPAg synthesis used variation AgNO3 0,1mM (F1); 0,5mM (F2) and 1,0mM (F3). Characterization using UV-Visible spektroscopy and Particle Size Analyzer (PSA). UV-Visible spektroscopy analysis showed that the NPAg at F2 and F3 in 400-500 nm wavelenght. The particle size used PSA at F1, F2 and F3 in 390,7 nm, 62,34 nm and 50,63 nm. F3 has been tested for antibacteial activity S.aureus, the result showed that the antibacterial activity at F3 much better than AgNO3 1,0 mM which is not nanometer scale.

PENAMBATAN MOLEKULER SENYAWA XANTON PADA KULIT BUAH MANGGIS (Garcinia Mangostana L.) DENGAN ENZIM COX-2 Sebagai Kandidat Antikanker Payudara. Herson Cahaya Himawan; Lilik Sulastri; Verari Vernando
Jurnal Farmamedika (Pharmamedika Journal) Vol 3 No 1 (2018): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Breast cancer is one of the most common types of cancer suffered by women around the world. Breast cancer is known that has relationship with chronic inflammation that is controlled by cyclooxygenase-2 (COX-2). Pericarp of mangosteen (Garcinia mangostana L.) contains a class compound of xanthone. The compound has potential as an inhibitor of the COX-2enzyme.The purpose of this research is to know the most active compound of xanthone compounds. Potential of xanthone compounds tested the toxicityby using Toxtree, the analysis of toxicity is focused on the carcinogenycity and mutagenicity.The result of toxicity test of ligand compound with Toxtree software found that the compound of 1-Isomangostin hydrate, 3-Isomangostin hydrate, Euxanthon, BR-xanthone A,Garcimangosone B and Garcimangosone D predicted safe for use as medicine. Then the compound itself analyzed based on the criteria of Lipinski's Rule of Five to predict the drug absorption in the human body. The analysis showed,five compounds fulfilled the criteria of Lipinski except Garcimangosone D. Further analysis was molecular docking using Autodock VinaA had a binding energy (ΔG) the best that was -10.1 kcal / mol if it compared to other test compounds, approaching the binding energy (ΔG) comparative compound of celecoxib -12.4 kcal / mol.

FORMULASI SEDIAAN GEL ANTIBAKTERI EKSTRAK ETANOL 70% DAUN BINTARO(Cerbera odollam Gaertn.) TERHADAP Staphylococcus aureus Ferry Effendi; Herson Cahaya Himawan; Firdhan Ausia Syahidin
Jurnal Farmamedika (Pharmamedika Journal) Vol 3 No 1 (2018): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Ethanol extract 70% of bintaro leaves could inhibit the growth of Staphylococcus aureus bacteria. Bintaro leaf extract (Cerbera odollam Gaertn) has chemical content of flavonoids, alkaloids and tannins. In this research was made preparation gel ethanol extract 70% from bintaro leaves (Cerbera odollam Gaertn.) and determine the formulation of gel preparation having good physical quality and have antibacterial effectivity. Physical quality tested such as homogeneity, organoleptic, viscosity, pH, spreadability, stability and antibacterial effectiveness test against Staphylococcus aureus bacteria using the disk diffusion method. The results showed that ethanol extract gel of 70% of bintaro leaves had good physical quality and best antibacterial effectiveness was found in Formulation III with 5% concentration. Based on one-way ANOVA analysis with Duncan assay, each formulation with different concentrations had a significant difference with α = 0.05.

EVALUASI STANDARD OPERATIONAL PROCEDURE PELAYANAN RESEP DI PUSKESMAS CIBUNGBULANG KABUPATEN BOGOR PERIODE MARET s/d APRIL 2018 Esa Nylidia; Muhammad Afqary; Ariyansyah
Jurnal Farmamedika (Pharmamedika Journal) Vol 3 No 1 (2018): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Prescription care is an integral part of pharmaceutical care at Primary Health Facility. Evaluation of prescription care standard at Primary Health Facility Cibungbulang was done by comparing the implementation of prescription care in Primary Health Facility with prescription prescribing standard according to Permenkes No 74 of 2016 about standard of pharmaceutical care at Primary Health Facility. A descriptive observational study was conducted on 324 samples. Data were collected using an observation table. The results showed that the date of prescribing, dosage, quantity of drug, rules of procedure and technique of use, accuracy of dose, time of drug use, preparation / compounding, delivery was done well with percentage of 100%. While other components such as patient id, paraf doctor, drug form, availability, drug side effects, label or etiquette, the provision of drug information that has not met the Pharmaceutical Care Standard in Primary Health Facility.

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Contact Name
Harry Noviardi

Contact Email
harry.noviardi@gmail.com

Phone
+622518323819

Journal Mail Official
lppm@sttif.ac.id

Editorial Address
Jl. Kumbang No.23, Bogor, Jawa Barat, 16151

Location
Kota bogor,

Jawa barat

INDONESIA

Abstract

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Harry Noviardi

Contact Email harry.noviardi@gmail.com

Phone +622518323819

Journal Mail Official lppm@sttif.ac.id

Editorial Address Jl. Kumbang No.23, Bogor, Jawa Barat, 16151

Location Kota bogor, Jawa barat INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Harry Noviardi

Contact Email
harry.noviardi@gmail.com

Phone
+622518323819

Journal Mail Official
lppm@sttif.ac.id

Editorial Address
Jl. Kumbang No.23, Bogor, Jawa Barat, 16151

Location
Kota bogor,

Jawa barat

INDONESIA